LOS ANGELES - Japanese two-way star Shohei Ohtani hit the 300th home run of his Major League Baseball career, reaching the mark at the fifth-fastest pace in history, as the Los Angeles Dodgers lost to the Colorado Rockies 4-3 on Tuesday.

Ohtani launched a 409-foot (125-meter) blast to center field off a 2-0 pitch from Rockies starter Michael Lorenzen in the first inning to register home runs in back-to-back games at Dodger Stadium.

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