Japanese scientist Shimon Sakaguchi and two Americans were awarded the Nobel Prize in Physiology or Medicine on Monday for their "groundbreaking" discoveries on how the immune system is kept in check, the Nobel Assembly at the Karolinska Institute said."The laureates' discoveries launched the field of peripheral tolerance, spurring the development of medical treatments for cancer and autoimmune diseases," the assembly said in a press release.Sakaguchi, a 74-year-old distinguished professor at Osaka University, discovered that regulatory T cells, or Tregs, prevent other T cells from attackin…READ FULL ARTICLE