A Japanese research team has found protein variants that increase during exercise and help burn fat, possibly opening a path to developing a new drug that helps people lose weight without dieting.The team's findings, published in the European scientific journal Molecular Metabolism, showed that different versions of the PGC-1a protein are produced in skeletal muscle when people exercise, and the larger the increase, the more energy people spend."An increase in PGC-1a expression, attributable mostly to upregulation of alternative variants, is pivotal for adaptive enhancement of energy expend…READ FULL ARTICLE