Takeda Pharmaceutical Co. said Wednesday it has raised its offer for acquiring Irish drugmaker Shire Plc. to $64 billion as it extended the deadline for what would be the biggest-ever overseas purchase by a Japanese company.Takeda raised its offer price per share to 49 pounds from 47 pounds in its fifth attempt to buy Shire, which would make the deal worth around 46 billion pounds.The deal would eclipse SoftBank Group Corp.'s 2016 purchase of British semiconductor designer ARM Holdings for 24 billion pounds -- the largest foreign acquisition by a Japanese company.The Japanese drugmaker said…READ FULL ARTICLE