Takeda Pharmaceutical Co. won approval from shareholders on Wednesday for its plan to purchase Irish drugmaker Shire Plc. for 46 billion pounds ($58 billion), the biggest-ever overseas acquisition by a Japanese company.Takeda overcame opposition from some of its founding family members and other stakeholders who cited hefty debt to finance the deal, and will become the world's ninth-largest drugmaker with combined sales of about 2.8 trillion yen ($24.8 billion).Nearly 90 percent of its shareholders approved the plan at an extraordinary meeting held in Osaka, Takeda said. Having already won …READ FULL ARTICLE